خ÷هيü يàنهويàے àïٍهêà نîٌٍàâèëà ہëهٌهيٌà ïًےىî يà نîى

[Pennynaide]

Alecnib (ہëهêٍèيèل) - ہëهêيèل (Alectinib) - àيàëîم ہëهٌهيٌà ًٌهنٌٍâî يîâîمî ïîêîëهيèے. خٍيîٌèٍüٌے نàييûé ïًهïàًàٍ ê êëèيèêî-ôàًىàêîëîمè÷هٌêîىَ ïîنêëàٌٌَ âهùهٌٍâ, êîٍîًûه لîً‏ٌٍے ٌ îïَُîëü‏, ïًهنîٍâًàùà‏ٍ è îٌٍàيàâëèâà‏ٍ هه ًàٌïًîًٌٍàيهيèه â îًمàيèçىه. دًهïàًàٍ èىههٍ âîçىîويîٌٍü لëîêèًîâàٍü ôهًىهيٍ ïًîٍهèيêèيàçû, ÷ٍî ٌïîٌîلٌٍâَهٍ îٌٍàيîâêه ًàٌïًîًٌٍàيهيè‏ îïَُîëهâûُ ٍêàيهé â îًمàيèçىه.

دîêàçàيèه ê ïًèىهيهيè‏
دًهïàًàٍ ïًèيèىàهٌٍے نëے لîًüلû ٌ ALK-ïîçèٍèâيûى يهىهëêîêëهٍî÷يûى ًàêîى ëهمêîمî. حà Alecnib (ہëهêٍèيèل) - ہëهêيèل (Alectinib) - àيàëîم ہëهٌهيٌà ِهيà َêàçàيà يà ٌàéٍه, âû ïًےىî ٌهé÷àٌ ىîوهٍه çàêàçàٍü همî ٌ نîٌٍàâêîé.

رïîٌîل ïًèىهيهيèے
خ÷هيü âàويî çيàٍü è ٌïîٌîل ïًàâèëüيîمî, ïًهنٌَىîًٍهييîمî èيًٌٍَêِèهé è ىهنèِèيٌêèى يàçيà÷هيèهى ïًèىهيهيèے ïًهïàًàٍà نëے لîëهه ‎ôôهêٍèâيîمî âîçنهéٌٍâèے يà îًمàيèçى ïàِèهيٍà. دًهونه âٌهمî, يàنî ٌêàçàٍü, ÷ٍî ëهêàًٌٍâهييîه ًٌهنٌٍâî ïًîèçâîنèٍüٌے è âûïٌَêàهٌٍے â êàïٌَëàُ, نëے âيًٍَهييهمî ïًèىهيهيèے. بُ يè â êîهى ٌëَ÷àه يهëüçے ًàٌêًûâàٍü è âûٌûïàٍü. رïîٌîل ïًèهىà ïهًîًàëüيûé. تàïٌَëَ يهîلُîنèىî çàمëàٍûâàٍü ِهëèêîى è çàïèٍü لîëüّèى êîëè÷هٌٍâîى âîنû, ïًîٍèâîïîêàçàيî çàïèâàٍü ïًهïàًàٍ مًهéïôًٍَîâûى ٌîêîى, ٍàê êàê ىîوهٍ ïًîèçîéٍè يهوهëàٍهëüيàے ُèىè÷هٌêàے ًهàêِèے نëے îًمàيèçىà. ؤîçèًîâêà çàâèٌèٍ îٍ ٍèïà ٍهًàïèè. رîمëàٌيî èيًٌٍَêِèè ïًîèçâîنèٍهëے ًهêîىهينَهٌٍے ïًèيèىàٍü ïî 600 ىم ïًهïàًàٍà (‎ٍî ًîâيî 4 ِهëûُ êàïٌَëû) نâàونû â ٌٍَêè âî âًهىے هنû. ؤëèٍهëüيîٌٍü êًٌَà نëèٌٍے نî يàٌٍَïëهيèے ïîëîوèٍهëüيîمî ‎ôôهêٍà, èëè هٌëè âîçيèêà‏ٍ ٌèëüيûه è ٍےوهëûه ïîلî÷يûه نهéٌٍâèے, ٍî ٍîمنà êًٌَ ïًهêًàùàهٌٍے.
زàê وه ïًè يهîلُîنèىîٌٍè âًà÷ ىîوهٍ ٌيèوàٍü نيهâيَ‏ نîçَ ïًهïàًàٍà إٌëè âàٌ èيٍهًهٌَهٍ يà Alecnib (ہëهêٍèيèل) - ہëهêيèل (Alectinib) - àيàëîم ہëهٌهيٌà ٌٍîèىîٌٍü[/b] è نîٌٍàâêà – çâîيèٍه, ىû âٌهمنà ًàنû ïîىî÷ü ٌ îôîًىëهيèهى çàêàçà.

دًîٍèâîïîêàçàيèے
تàê è ë‏لîé ïًهïàًàٍ, هٌٍü مًَïïû ëèِ, êîٍîًûى îي ïًîٍèâîïîêàçàي ٌëهنَ‏ùèى, ê ٍàêèى مًَïïàى ëèِ îٍيîٌےٌٍے: • ثèِà, èىه‏ùèه يهïهًهيîٌèىîٌٍü ê ë‏لûى êîىïîيهيٍàى èç ٌîٌٍàâà ëهêàًٌٍâهييîمî ًٌهنٌٍâà; • ثèِà نî âîٌهىيàنِàٍè ëهٍ, âûيàّèâà‏ùèه ًهلهيêà è êîًىےùèه مًَنü‏; • ثèِà, َ êîٍîًûُ èىههٌٍے ٍےوهëàے ïî÷ه÷يàے يهنîٌٍàٍî÷يîٌٍü; • ثèِà, êîٍîًûى يهîلُîنèى مهىîنèàëèç.

دîلî÷يûه ‎ôôهêٍû
آ ِهëîى ïًî Alecnib (ہëهêٍèيèل) - ہëهêيèل (Alectinib) - àيàëîم ہëهٌهيٌà îٍçûâû âًٌٍه÷à‏ٌٍے ïîëîوèٍهëüيûه. حî èيîمنà â ïًîِهٌٌه ïًèىهيهيèے َ îًمàيèçىà ىîمٍَ âîçيèêيٍَü يهمàٍèâيûه ًهàêِèè يà ïًهïàًàٍ, à èىهييî - âîçىîويî ïîًàوهيèه èيôهêِèهé, يàلë‏نهيèه ًهçêîمî ٌïàنà àïïهٍèٍà, ََُنّهيèے çًèٍهëüيîé ôَيêِèهé îًمàيèçىà, مîëîâîêًَوهيèه è ïîےâëهيèه مîëîâيûُ لîëهé. آîçىîويî, لَنهٍ ïîâûّàٍüٌے àًٍهًèàëüيîه نàâëهيèه, è îلًàçîâûâàٍüٌے مهىàٍîىû. حهمàٍèâيàے ُèىè÷هٌêàے ًهàêِèے ىîوهٍ âûçâàٍü è âîٌïàëهيèے ٌëèçèٌٍîé ًٍà, لîëè â لً‏ّيîé ïîëîٌٍè, ًàًٌٌٍîéٌٍâî وهëَنêà, âٌëهنٌٍâèه ÷همî لَنهٍ يهيîًىàëüيûé ٌٍَë. ءîëهâûه îùَùهيèے â ىûِّàُ è ٌٌٍَàâàُ, à ٍàêوه ٌيèوهيèه âهٌà, يàًَّهيèے êîويûُ ïîêًîâîâ, îٍهê يèويèُ êîيه÷يîٌٍهé, îنûّêà è êàّهëü. إٌëè âàى يَويî Alecnib (ہëهêٍèيèل) - ہëهêيèل (Alectinib) - àيàëîم ہëهٌهيٌà êَïèٍü نهّهâî – ونهى âàّهمî çâîيêà.


àëهêٍèيèل êَïèٍü

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